Robert W Aldridge, Dee Menezes, Dan Lewer, Michelle Cornes, Hannah Evans, Ruth M Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, James Fuller, others.
data in England.[version 1; referees: awaiting peer review].
2021.
José Machado, António Abelha, Manuel Filipe Santos, Filipe Portela, Abdelali Boussadi, Alejandro Rodrı́guez González, Alexandros T Tzallas, Antonio Dourado, Evanthia E Tripoliti, Fabien Scalzo, others.
ISAHealth 2016 Organizing Committee.
2021.
John M Dennis, Bilal A Mateen, Raphael Sonabend, Nicholas J Thomas, Kashyap A Patel, Andrew T Hattersley, Spiros Denaxas, Andrew P McGovern, Sebastian J Vollmer.
Type 2 diabetes and COVID-19--Related mortality in the critical care setting: a national cohort study in England, March--July 2020.
Diabetes Care,
2021.
Victoria Garfield, Aliki-Eleni Farmaki, Ghazaleh Fatemifar, Sophie V Eastwood, Rohini Mathur, Christopher T Rentsch, Spiros Denaxas, Krishnan Bhaskaran, Liam Smeeth, Nish Chaturvedi.
The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomisation study in the UK Biobank.
Diabetes,
2021.
Harrison Wilde, Thomas Mellan, Iwona Hawryluk, John M Dennis, Spiros Denaxas, Christina Pagel, Andrew Duncan, Samir Bhatt, Seth Flaxman, Bilal A Mateen, others.
The association between mechanical ventilator availability and mortality risk in intensive care patients with COVID-19: A national retrospective cohort study.
medRxiv,
2021.
Alicia Uijl, Ilonca Vaartjes, Spiros Denaxas, Harry Hemingway, Anoop Shah, John Cleland, Diederick Grobbee, Arno Hoes, Folkert W Asselbergs, Stefan Koudstaal.
Temporal trends in heart failure medication prescription in a population-based cohort study.
BMJ open,
2021.
Jane Lyons, Ashley Akbari, Utkarsh Agrawal, Gill Harper, Amaya Azcoaga-Lorenzo, Rowena Bailey, James Rafferty, Alan Watkins, Richard Fry, Colin McCowan, others.
Protocol for the development of the Wales Multimorbidity e-Cohort (WMC): data sources and methods to construct a population-based research platform to investigate multimorbidity.
BMJ open,
2021.
Angela Wood, Rachel Denholm, Sam Hollings, Jennifer Anne Cooper, Samantha Ip, Venexia Walker, Spiros Denaxas, Ashley Akbari, Jonathan Sterne, Cathie Sudlow, others.
Linking electronic health records for research on a nationwide cohort including over 54 million people in England.
medRxiv,
2021.
Catherine M Smith, Laura J Shallcross, Peter Dutey-Magni, Anne Conolly, Christopher Fuller, Suzanne Hill, Arnoupe Jhass, Franziska Marcheselli, Susan Michie, Jennifer S Mindell, others.
Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study.
BMC infectious diseases,
2021.
Michail Katsoulis, Alvina Lai, Karla Diaz-Ordaz, Manuel Gomes, Laura Pasea, Amitava Banerjee, Spiros Denaxas, Kostas Tsilidis, Pagona Lagiou, Gesthimani Misirli, others.
Identifying high-risk groups for change in weight and body mass index: population cohort of 11 million measurements in 2.3 million adults.
medRxiv,
2021.
Dan Lewer, Dee Menezes, Michelle Cornes, Ruth M Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, Hannah Evans, James Fuller, Nigel Hewett, others.
Hospital readmission among people experiencing homelessness in England: a cohort study of 2772 matched homeless and housed inpatients.
J Epidemiol Community Health,
2021.
PF Dutey-Magni, MJ Gill, D McNulty, G Sohal, A Hayward, L Shallcross, Niall Anderson, Elise Crayton, Gillian Forbes, Arnoupe Jhass, others.
Feasibility study of hospital antimicrobial stewardship analytics using electronic health records.
JAC-Antimicrobial Resistance,
2021.
Valerie Kuan, Helen C Fraser, Melanie Hingorani, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Dorothea Nitsch, Rohini Mathur, Constantinos A Parisinos, R Thomas Lumbers, others.
Data-driven identification of ageing-related diseases from electronic health records.
Scientific reports,
2021.
Alvina G Lai, Wai Hoong Chang, Constantinos A Parisinos, Michail Katsoulis, Ruth M Blackburn, Anoop D Shah, Vincent Nguyen, Spiros Denaxas, George Davey Smith, Tom R Gaunt, others.
An Informatics Consult approach for generating clinical evidence for treatment decisions.
medRxiv,
2021.
Harrison A Wilde, Thomas A Mellan, Iwona Hawryluk, John Dennis, Spiros Denaxas, Christina Pagel, Andrew Duncan, Samir Bhatt, Seth Flaxman, Bilal A Mateen, others.
A national retrospective cohort study of mechanical ventilator availability and its association with mortality risk in intensive care patients with COVID-19.
medRxiv,
2021.
Samuel JRA Chawner, Joanne L Doherty, Richard JL Anney, Kevin M Antshel, Carrie E Bearden, Raphael Bernier, Wendy K Chung, Caitlin C Clements, Sarah R Curran, Goran Cuturilo, others.
A genetics-first approach to dissecting the heterogeneity of autism: phenotypic comparison of autism risk copy number variants.
American Journal of Psychiatry,
2021.
Michail Katsoulis, Bianca DeStavola, Karla Diaz-Ordaz, Manuel Gomes, Alvina Lai, Pagona Lagiou, Goya Wannamethee, Kostas Tsilidis, Tom Lumbers, Spiros Denaxas, others.
Weight change and the incidence of cardiovascular diseases in adults with normal weight, overweight and obesity without chronic diseases; emulating trials using electronic health records.
medRxiv,
2020.
John M Dennis, Bilal A Mateen, Raphael Sonabend, Nicholas J Thomas, Kashyap A Patel, Andrew T Hattersley, Spiros Denaxas, Andrew P McGovern, Sebastian J Vollmer.
Type 2 Diabetes and COVID-19--Related Mortality in the Critical Care Setting: A National Cohort Study in England, March--July 2020.
Diabetes Care,
2020.
Victoria Garfield, Aliki-Eleni Farmaki, Ghazaleh Fatemifar, Sophie V Eastwood, Rohini Mathur, Christopher T Rentsch, Spiros Denaxas, Krishnan T Bhaskaran, Liam Smeeth, Nish Chaturvedi.
The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK Biobank.
medRxiv,
2020.
Simon Ball, Amitava Banerjee, Colin Berry, Jonathan Boyle, Benjamin Bray, William Bradlow, Afzal Chaudhry, Rikki Crawley, John Danesh, Alastair Denniston, others.
The 4C Initiative (Clinical Care for Cardiovascular disease in the COVID-19 pandemic): monitoring the indirect impact of the coronavirus pandemic on services for cardiovascular diseases in the UK.
medRxiv,
2020.
Richard Gale, Claire Gill, Maria Pikoula, Aaron Y Lee, Rachel LW Hanson, Spiros Denaxas, Catherine Egan, Adnan Tufail, Paul Taylor, others.
Multicentre study of 4626 patients assesses the effectiveness, safety and burden of two categories of treatments for central retinal vein occlusion: intravitreal anti-vascular endothelial growth factor injections and intravitreal Ozurdex injections.
British Journal of Ophthalmology,
2020.
Simon Ball, Amitava Banerjee, Colin Berry, Jonathan R Boyle, Benjamin Bray, William Bradlow, Afzal Chaudhry, Rikki Crawley, John Danesh, Alastair Denniston, others.
Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK.
Heart,
2020.
Max T Eyre, Rachel Burns, Victoria Kirkby, Catherine Smith, Spiros Denaxas, Vincent Nguyen, Andrew Hayward, Laura Shallcross, Ellen Fragaszy, Robert W Aldridge.
Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study.
Wellcome Open Research,
2020.
Spiros Denaxas, A Miguel.
IEA.
International Journal of Epidemiology,
2020.
Michail Katsoulis, Alvina G Lai, Dimitra-Kleio Kipourou, Reecha Sofat, Manuel Gomes, Amitava Banerjee, Spiros Denaxas, Thomas R Lumbers, Kostas Tsilidis, Harry Hemingway, others.
How to estimate the association between change in a risk factor and a health outcome?.
arXiv preprint arXiv:2012.11291,
2020.
Neha Pathak, Parth Patel, Rachel Burns, Lucinda Haim, Claire X Zhang, Yamina Boukari, Arturo Gonzales-Izquierdo, Rohini Mathur, Caroline Minassian, Alexandra Pitman, others.
Healthcare resource utilisation and mortality outcomes in international migrants to the UK: analysis protocol for a linked population-based cohort study using Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the Office for National Statistics (ONS).
Wellcome Open Research,
2020.
Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, Åsa K Hedman, Jemma B Wilk, Michael P Morley, Mark D Chaffin, others.
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Nature communications,
2020.
Amitava Banerjee, Suliang Chen, Laura Pasea, Alvina Lai, Michail Katsoulis, Spiros Denaxas, Vahe Nafilyan, Bryan Williams, Wai Keong Wong, Ameet Bakhai, others.
Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic..
medRxiv,
2020.
Michail Katsoulis, Manuel Gomes, Alvina G Lai, Albert Henry, Spiros Denaxas, Pagona Lagiou, Vahe Nafilyan, Ben Humberstone, Amitava Banerjee, Harry Hemingway, others.
Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic.
Circulation: Cardiovascular Quality and Outcomes,
2020.
Amitava Banerjee, Laura Pasea, Steve Harris, Arturo Gonzalez-Izquierdo, Ana Torralbo, Laura Shallcross, Mahdad Noursadeghi, Deenan Pillay, Neil Sebire, Chris Holmes, others.
Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study.
The Lancet,
2020.
Alvina G Lai, Laura Pasea, Amitava Banerjee, Geoff Hall, Spiros Denaxas, Wai Hoong Chang, Michail Katsoulis, Bryan Williams, Deenan Pillay, Mahdad Noursadeghi, others.
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open,
2020.
Amitava Banerjee, Michail Katsoulis, Alvina G Lai, Laura Pasea, Thomas A Treibel, Charlotte Manisty, Spiros Denaxas, Giovanni Quarta, Harry Hemingway, Joao Cavalcante, others.
Clinical academic research in the time of Corona: a simulation study in England and a call for action.
medRxiv,
2020.
Samden D Lhatoo, Neda Bernasconi, Ingmar Blumcke, Kees Braun, Jeffrey Buchhalter, Spiros Denaxas, Aristea Galanopoulou, Colin Josephson, Katja Kobow, Daniel Lowenstein, others.
Big data in epilepsy: clinical and research considerations. Report from the Epilepsy Big Data Task Force of the International League Against Epilepsy.
Epilepsia,
2020.
Laura Shallcross, Fabiana Lorencatto, Christopher Fuller, Carolyn Tarrant, Jonathan West, Rosanna Traina, Catherine Smith, Gillian Forbes, Elise Crayton, Patrick Rockenschaub, others.
An interdisciplinary mixed-methods approach to developing antimicrobial stewardship interventions: Protocol for the Preserving Antibiotics through Safe Stewardship (PASS) Research Programme.
Wellcome Open Research,
2020.
Harry Hemingway, Ronan Lyons, Qianrui Li, Iain Buchan, John Ainsworth, Jill Pell, Andrew Morris, Michael R Barnes, Helen Bedford, Marion Bennie, others.
A national initiative in data science for health: an evaluation of the UK Farr Institute.
International journal of population data science,
2020.
A Banerjee, L Pasea, SC Chung, K Direk, FW Asselbergs, S Denaxas, H Hemingway.
92 aetiologic factors for heart failure: prevalence, co-occurrence, prognosis and potential for prevention in 170,885 incident HF cases.
European Heart Journal,
2020.
Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Natalie K Fitzpatrick, Ghazaleh Fatemifar, Amitava Banerjee, Richard JB Dobson, Laurence J Howe, Valerie Kuan, R Tom Lumbers, others.
UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER.
Journal of the American Medical Informatics Association,
2019.
Maurı́cio Lima Barreto, Maria Yury Travassos Ichihara, Bethânia de Araújo Almeida, Marcos Ennes Barreto, L Cabral, Rosemeire Leovigildo Fiaccone, Roberto Perez Carreiro, Carlos Antonio de Souza Teles, Ivan da Rocha Pitta, Gerson Oliveira Penna, others.
The Centre for Data and Knowledge Integration for Health (CIDACS): Linking Health and Social Data in Brazil.
Swansea University,
2019.
Amitava Banerjee, Victoria Allan, Spiros Denaxas, Anoop Shah, Dipak Kotecha, Pier D Lambiase, Jacob Joseph, Lars H Lund, Harry Hemingway.
Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis.
EP Europace,
2019.
Elizabeth Williamson, Spiros Denaxas, Steve Morris, C Clarke, Mike Thomas, Hannah Evans, Kenan Direk, Arturo Gonzalez-Izquierdo, Paul Little, Valerie Lund, others.
Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records.
Rhinology,
2019.
Amand F Schmidt, Michael V Holmes, David Preiss, Daniel I Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, others.
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
BMC cardiovascular disorders,
2019.
Aroon D Hingorani, Valerie Kuan, Chris Finan, Felix A Kruger, Anna Gaulton, Sandesh Chopade, Reecha Sofat, Raymond J MacAllister, John P Overington, Harry Hemingway, others.
Improving the odds of drug development success through human genomics: modelling study.
Scientific Reports,
2019.
Dan Lewer, Dee Menezes, Michelle Cornes, Ruth Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, Hannah Evans, James Fuller, Nigel Hewett, others.
Hospital Readmissions Among People Experiencing Homelessness: A Cohort Study of Linked Hospitalisation and Mortality Data in England for 3,222 Homeless Inpatients.
2019.
Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, Åsa K Hedman, Jemma B Wilk, Michael P Morley, Mark D Chaffin, others.
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure.
bioRxiv,
2019.
Jane Vennik, Helen Blackshaw, Carl Philpott, Mike Thomas, Caroline Eyles, James Carpenter, Caroline S Clarke, Stephen Morris, Anne Schilder, Valerie Lund, others.
Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme)..
2019.
Helen Blackshaw, Jane Vennik, Carl Philpott, Mike Thomas, Caroline Eyles, James Carpenter, Caroline S Clarke, Steve Morris, Anne Schilder, Valerie Lund, others.
Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).
Trials,
2019.
Emelia J Benjamin, Paul Muntner, Alvaro Alonso, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Alexander R Chang, Susan Cheng, Sandeep R Das, others.
Employment Cost Index, Historical Listing--Volume V: Continuous Occupational and Industry Series: September 1975-December 2017. Table 4: employment cost index for total compensation, for civilian workers, by occupation and industry: continuous occupational and industry series..
Circulation,
2019.
Maxine Mackintosh, Rob W Aldridge, Martin Rossor, Arturo Gonzalez-Izquierdo, Kirstie J Whitaker, Elizabeth Ford, Kenan Direk, Spiros Denaxas.
Dementia recognition, diagnosis, and treatment in the UK, 1997--2017: a change-point analysis.
The Lancet,
2019.
Carl Philpott, Steffi Le Conte, David Beard, Jonathan Cook, William Sones, Steve Morris, Caroline S Clarke, Mike Thomas, Paul Little, Jane Vennik, others.
Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial.
Trials,
2019.
Robert W Aldridge, Dee Menezes, Dan Lewer, Michelle Cornes, Hannah Evans, Ruth M Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, James Fuller, others.
Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England..
Wellcome open research,
2019.
Laura Pasea, Sheng-chia Chung, Mar Pujades-Rodriguez, Anoop D Shah, Samantha Alvarez-Madrazo, Victoria Allan, James T Teo, Daniel Bean, Reecha Sofat, Richard Dobson, others.
Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis.
BMC medicine,
2019.
Ruth E Farmer, Rohini Mathur, A Floriaan Schmidt, Krishnan Bhaskaran, Ghazaleh Fatemifar, Sophie V Eastwood, Chris Finan, Spiros Denaxas, Liam Smeeth, Nish Chaturvedi.
Associations between measures of sarcopenic obesity and risk of cardiovascular disease and mortality: a cohort study and Mendelian randomization analysis using the UK Biobank.
Journal of the American Heart Association,
2019.
Claire Hopkins, Elizabeth Williamson, Steve Morris, Caroline S Clarke, Mike Thomas, Hannah Evans, Paul Little, Valerie J Lund, Helen Blackshaw, Anne Schilder, others.
Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records.
Rhinology,
2019.
Valerie Kuan, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Osman Bhatti, Shanaz Husain, Shailen Sutaria, Melanie Hingorani, Dorothea Nitsch, Constantinos A Parisinos, others.
A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service.
The Lancet Digital Health,
2019.
M Pikoula, JK Quint, K Direk, F Nissen, A Gonzalez-Izquierdo, H Hemingway, L Smeeth, S Denaxas.
Discovery of Novel COPD Subtypes Via Cluster Analysis of Clinical Features Extracted from Electronic Health Records.
D13. IMPROVING DIAGNOSIS, CARE QUALITY, AND ADHERENCE IN COPD,
2018.
Steve Harris, Sinan Shi, David Brealey, Niall S MacCallum, Spiros Denaxas, David Perez-Suarez, Ari Ercole, Peter Watkinson, Andrew Jones, Simon Ashworth, others.
Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database.
International Journal of Medical Informatics,
2018.
Johannes MIH Gho, Amand F Schmidt, Laura Pasea, Stefan Koudstaal, Mar Pujades-Rodriguez, Spiros Denaxas, Anoop D Shah, Riyaz S Patel, Chris P Gale, Arno W Hoes, others.
An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors.
BMJ open,
2018.
Kim McGrail, Kerina Jones, Ashley Akbari, Tell Bennett, Andrew Boyd, Fabrizio Carinci, Xinjie Cui, Spiros Denaxas, Nadine Dougall, David Ford, others.
A Position Statement on Population Data Science: The science of data about people.
International Journal of Population Data Science,
2018.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Summary of published papers relating to individual studies in the programme.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Stable coronary artery disease: risk prediction and cost-effective targeting of interventions.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Risk factor modification among people without established cardiovascular disease.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Programme grants for applied research.
Using Nationwide �Big Data�from Linked Electronic Health Records to Help Improve Outcomes in Cardiovascular Diseases,
2017.
Stefan Koudstaal, Mar Pujades-Rodriguez, Spiros Denaxas, Johannes MIH Gho, Anoop D Shah, Ning Yu, Riyaz S Patel, Chris P Gale, Arno W Hoes, John G Cleland, others.
Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people.
European journal of heart failure,
2017.
Clicia Pinto, Robespierre Pita, George Barbosa, Bruno Araújo, Juracy Bertoldo, Samila Sena, Sandra Reis, Rosemeire Fiaccone, Leila Amorim, Maria Yuri Ichihara, others.
Probabilistic integration of large Brazilian socioeconomic and clinical databases.
2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS),
2017.
Laura Pasea, Sheng-chia Chung, Mar Pujades-Rodriguez, Alireza Moayyeri, Spiros Denaxas, Keith AA Fox, Lars Wallentin, Stuart J Pocock, Adam Timmis, Amitava Banerjee, others.
Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors.
European heart journal,
2017.
Ruth M Blackburn, Andrew Hayward, Michelle Cornes, Martin McKee, Dan Lewer, Martin Whiteford, Dee Menezes, Serena Luchenski, Alistair Story, Spiros Denaxas, others.
Outcomes of specialist discharge coordination and intermediate care schemes for patients who are homeless: analysis protocol for a population-based historical cohort.
BMJ open,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Inequalities in the incidence of 12 cardiovascular diseases across the patient journey.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
A Hingorani, Valerie Kuan, Chris Finan, F Kruger, Anna Gaulton, Sandesh Chopade, Reecha Sofat, R MacAllister, John Overington, Harry Hemingway, others.
Flipping the odds of drug development success through human genomics.
bioRxiv,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Conclusions and implications for clinical practice and further research.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
Harry Hemingway, Folkert W Asselbergs, John Danesh, Richard Dobson, Nikolaos Maniadakis, Aldo Maggioni, Ghislaine JM van Thiel, Maureen Cronin, Gunnar Brobert, Panos Vardas, others.
Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.
European Heart Journal,
2017.
Steven Bell, Marina Daskalopoulou, Eleni Rapsomaniki, Julie George, Annie Britton, Martin Bobak, Juan P Casas, Caroline E Dale, Spiros Denaxas, Anoop D Shah, others.
Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.
BMJ,
2017.
Harry Hemingway, Gene S Feder, Natalie K Fitzpatrick, Spiros Denaxas, Anoop D Shah, Adam D Timmis.
Acute myocardial infarction: missed opportunities for treatment during and after hospitalisation.
Using nationwide �big data�from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme,
2017.
Eleni Rapsomaniki, Marcus Thuresson, Erru Yang, Patrick Blin, Phillip Hunt, Sheng-chia Chung, Dimitris Stogiannis, Mar Pujades-Rodriguez, Adam Timmis, Spiros C Denaxas, others.
Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction.
European Heart Journal-Quality of Care and Clinical Outcomes,
2016.
A Timmis, E Rapsomaniki, SC Chung, M Pujades-Rodriguez, A Moayyeri, D Stogiannis, AD Shah, L Pasea, S Denaxas, C Emmas, others.
Prolonged dual antiplatelet therapy in stable coronary disease: comparative observational study of benefits and harms in unselected versus trial populations.
bmj,
2016.
S Koudstaal, M Pujades-Rodriguez, S Denaxas, JMIH Gho, A Shah, C Gale, A Hoes, J Cleland, F Asselbergs, H Hemingway.
Prognostic burden of heart failure diagnosed in primary care or secondary care: a population-based linked electronic health record cohort study in 2.1 million people: 675.
European Journal of Heart Failure,
2016.
A Moayyeri, R Patel, M Pujades-Rodriguez, S Denaxas, A Banerjee, V Allan, K Direk, D Prieto-Merino, FW Asselbergs, AD Hingorani, others.
Low levels of LDL-cholesterol and incidence of a wide range of cardiovascular diseases: a linked electronic health records cohort of 550,000 people.
2016.
S Denaxas, CP Friedman, A Geissbuhler, H Hemingway, D Kalra, M Kimura, KA Kuhn, TH Payne, FGB de Quiros, JC Wyatt.
Discussion of'Combining Health Data Uses to Ignite Health System Learning'(vol 54, pg 488, 2015).
METHODS OF INFORMATION IN MEDICINE,
2016.
Marina Daskalopoulou, Julie George, Kate Walters, David P Osborn, G David Batty, Dimitris Stogiannis, Eleni Rapsomaniki, Mar Pujades-Rodriguez, Spiros Denaxas, Ruzan Udumyan, others.
Depression as a risk factor for the initial presentation of twelve cardiac, cerebrovascular, and peripheral arterial diseases: data linkage study of 1.9 million women and men.
PloS one,
2016.
Shang-Ming Zhou, Fabiola Fernandez-Gutierrez, Jonathan Kennedy, Roxanne Cooksey, Mark Atkinson, Spiros Denaxas, Stefan Siebert, William G Dixon, Terence W O�Neill, Ernest Choy, others.
Defining disease phenotypes in primary care electronic health records by a machine learning approach: a case study in identifying rheumatoid arthritis.
PloS one,
2016.
Bruna Rubbo, Natalie K Fitzpatrick, Spiros Denaxas, Marina Daskalopoulou, Ning Yu, Riyaz S Patel, UK Biobank Follow-up, Harry Hemingway, Outcomes Working Group, others.
Use of electronic health records to ascertain, validate and phenotype acute myocardial infarction: A systematic review and recommendations.
International journal of cardiology,
2015.
Anoop Dinesh Shah, Claudia Langenberg, Eleni Rapsomaniki, Spiros Denaxas, Mar Pujades-Rodriguez, Chris P Gale, John Deanfield, Liam Smeeth, Adam Timmis, Harry Hemingway.
Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1˙ 9 million people.
The Lancet Diabetes & endocrinology,
2015.
Rachel Johnson, Maggie Evans, Helen Cramer, Kristina Bennert, Richard Morris, Sandra Eldridge, Katy Juttner, Mohammed J Zaman, Harry Hemingway, Spiros Denaxas, others.
Feasibility and impact of a computerised clinical decision support system on investigation and initial management of new onset chest pain: a mixed methods study.
BMC medical informatics and decision making,
2015.
S Denaxas, CP Friedman, Antoine Geissbuhler, H Hemingway, D Kalra, M Kimura, KA Kuhn, HA Payne, FG de Quiros, JC Wyatt.
Discussion of �combining health data uses to ignite health system learning.�.
Methods Inf Med,
2015.
Tito Castillo, Arofan Gregory, Samuel Moore, Brian Hole, Christiana McMahon, Spiros Denaxas, Veerle van Den Eyden, Herve L'Hours, Lucy Bell, Jack Kneeshaw, others.
Wellcome Trust: Enhancing Discoverability of Public Health and Epidemiology Research Data.
Wellcome Trust,
2014.
Eleni Rapsomaniki, Anoop Shah, Pablo Perel, Spiros Denaxas, Julie George, Owen Nicholas, Ruzan Udumyan, Gene Solomon Feder, Aroon D Hingorani, Adam Timmis, others.
Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients.
European heart journal,
2014.
E Rapsomaniki, D Stogiannis, C Emmas, S Chung, L Pasea, S Denaxas, AD Shah, M Pujades-Rodriguez, A Timmis, H Hemingway.
Health outcomes in patients with stable coronary artery disease following myocardial infarction; construction of a PEGASUS-TIMI-54 like population in UK linked electronic health records.
EUROPEAN HEART JOURNAL,
2014.
Katherine I Morley, Joshua Wallace, Spiros C Denaxas, Ross J Hunter, Riyaz S Patel, Pablo Perel, Anoop D Shah, Adam D Timmis, Richard J Schilling, Harry Hemingway.
Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation.
PloS one,
2014.
Eleni Rapsomaniki, Adam Timmis, Julie George, Mar Pujades-Rodriguez, Anoop D Shah, Spiros Denaxas, Ian R White, Mark J Caulfield, John E Deanfield, Liam Smeeth, others.
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1˙ 25 million people.
The Lancet,
2014.
Spiros C Denaxas, Dipak Kalra, Eleni Rapsomaniki, A Shah, Mar Pujades-Rodriguez, Katherine Morley, Adam Timmis, Emily Herrett, Liam Smeeth, Harry Hemingway.
Electronic Health Record Linkages for Translational Cardiovascular Research in Nearly 2 Million People-Clinical Disease Research Using Linked Bespoke Studies and Electronic Records (CALIBER)..
AMIA,
2013.
Emily Herrett, Anoop Dinesh Shah, Rachael Boggon, Spiros Denaxas, Liam Smeeth, Tjeerd van Staa, Adam Timmis, Harry Hemingway.
Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study.
BMJ,
2013.
M Asaria, S Walker, MJ Sculpher, S Palmer, A Manca, KR Abrams, H Hemingway, S Denaxas, KI Morley, A Shah, others.
Challenges of conducting economic evaluations using linked electronic health records-CPRD and HES in the United Kingdom.
Value in Health,
2013.
Julie George, Emily Herrett, Spiros Denaxas, Owen Nicholas, Anoop Shah, Eleni Rapsomaniki, Jinqi Zhang, Adam Timmis, Liam Smeeth, Harry Hemingway.
Differential Effects of Smoking on Specific Cardiovascular Presentations in Men and Women: Prospective Cohort Study in 900,000 Patients Using CALIBER Linked Electronic Health Records.
Lippincott Williams & Wilkins,
2012.
Spiros C Denaxas, Julie George, Emily Herrett, Anoop D Shah, Dipak Kalra, Aroon D Hingorani, Mika Kivimaki, Adam D Timmis, Liam Smeeth, Harry Hemingway.
Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER).
International journal of epidemiology,
2012.