Publications

Clustering Long-Term Health Conditions Among 67728 People with Multimorbidity Using Electronic Health Records in Scotland. 2023.

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Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19--a data-driven retrospective cohort study. Journal of the Royal Society of Medicine, 2023.

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Translating and evaluating historic phenotyping algorithms using SNOMED CT. Journal of the American Medical Informatics Association, 2023.

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Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond. Journal of the American Medical Informatics Association, 2023.

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The relationship between adiposity and cognitive function: a bidirectional Mendelian randomization study in UK Biobank. International Journal of Epidemiology, 2023.

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The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nature Medicine, 2023.

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Phenotyping with positive unlabelled learning for genome-wide association studies. Multimodal AI in Healthcare, 2023.

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Neurodevelopmental dimensional assessment of young children at high genomic risk of neuropsychiatric conditions. JCPP Advances, 2023.

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Medical history predicts phenome-wide disease onset. medRxiv, 2023.

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Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals. Alzheimer’s & Dementia, 2023.

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Impact on life expectancy of temporal sequencing in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure using linked data for 1.7 million individuals in Wales with 20-year follow-up. The Lancet Public Health, 2023.

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Identifying subtypes of chronic kidney disease with machine learning: development, internal validation and prognostic validation using linked electronic health records in 350,067 individuals. EBioMedicine, 2023.

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Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. The Lancet Digital Health, 2023.

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Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration. BMC Medical Informatics and Decision Making, 2023.

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Diffsurv: Differentiable sorting for censored time-to-event data. arXiv preprint arXiv:2304.13594, 2023.

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Determining prescriptions in electronic health care (EHR) studies: methods for development of standardised, reproducible drug codelists. medRxiv, 2023.

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Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study. European Journal of Preventive Cardiology, 2023.

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Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study. EClinicalMedicine, 2023.

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Identifying Subtypes of Chronic Kidney Disease with Machine Learning: Development, Internal Validation and Prognostic Validation Using Electronic Health Records in 350067 Individuals. Internal Validation and Prognostic Validation Using Electronic Health Records in, 2022.

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A retrospective cohort study predicting and validating impact of the COVID-19 pandemic in individuals with chronic kidney. 2022.

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A Complex Systems Perspective on Macroprudential Regulation.. Handbook of Financial Stress Testing, 2022.

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Using National Electronic Health Records for Pandemic Preparedness: Validation of a Parsimonious Model for Predicting Excess Deaths Among Those With COVID-19. 2022.

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UK phenomics platform for developing and validating EHR phenotypes: CALIBER. J Am Med Inf, 2022.

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Predicting and Validating Risk of Pre-Pandemic and Excess Mortality in Individuals With Chronic Kidney Disease. 2022.

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Translating and evaluating historic phenotyping algorithms using SNOMED CT. Journal of the American Medical Informatics Association, 2022.

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Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond. Journal of the American Medical Informatics Association, 2022.

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The Relationship between Adiposity and Cognitive Function: A Bidirectional Mendelian Randomization Study in UK Biobank. GENETIC EPIDEMIOLOGY, 2022.

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The adverse impact of COVID-19 pandemic on cardiovascular disease prevention and management in England, Scotland and Wales: A population-scale descriptive analysis of trends in medication data. medRxiv, 2022.

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Temporal sequencing in multimorbidity using population-scale linked data for 1.7 million individuals with 20-year follow-up. 2022.

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Risk of myocarditis and pericarditis following COVID-19 vaccination in England and Wales. medRxiv, 2022.

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Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. bmj, 2022.

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Rare and common genetic determinants of metabolic individuality and their effects on human health. Nature Medicine, 2022.

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Publisher Correction: Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. Nature Medicine, 2022.

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POS-283 HIERARCHICAL CLUSTERING FOR SUBTYPE DISCOVERY OF INCIDENT CHRONIC KIDNEY DISEASE FROM LARGE LONGITUDINAL ELECTRONIC HEALTH RECORDS. Kidney International Reports, 2022.

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POS-282 ASSOCIATION BETWEEN PRIMARY CARE CODING OF CHRONIC KIDNEY DISEASE (CKD) AND SUBSEQUENT HOSPITALISATIONS AND DEATH: A COHORT ANALYSIS USING NATIONAL AUDIT DATA. Kidney International Reports, 2022.

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Phenotyping with Positive Unlabelled Learning for Genome-Wide Association Studies. arXiv preprint arXiv:2202.07451, 2022.

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Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thrombocytopenia in Real World Data: A Multinational Network Cohort Study. Drug Safety, 2022.

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Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature. Frontiers in psychology, 2022.

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Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature. Frontiers in psychology, 2022.

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Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature. Frontiers Media, 2022.

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Observational retrospective study calculating health service costs of patients receiving surgery for chronic rhinosinusitis in England, using linked patient-level primary and secondary care electronic data. BMJ open, 2022.

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Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study. The Lancet Psychiatry, 2022.

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Neural-Signature Methods for Structured EHR Prediction. 2022.

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Long-Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study. Journal of the American Heart Association, 2022.

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Lifetime risk of cardiovascular-renal disease in type 2 diabetes: a population-based study in 473,399 individuals. BMC medicine, 2022.

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Late-onset epilepsy and risk of premature death: the complex role of comorbidities. EPILEPSIA, 2022.

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Indirect effects of the first two years of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries.. medRxiv, 2022.

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Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals. Alzheimer’s & Dementia, 2022.

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Identifying subtypes of heart failure with machine learning: external, prognostic and genetic validation in three electronic health record sources with 320,863 individuals. medRxiv, 2022.

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Identification and mapping real-world data sources for heart failure, acute coronary syndrome, and atrial fibrillation. Cardiology, 2022.

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Healthcare costs for patients receiving surgery for chronic rhinosinusitis in England, using linked primary and secondary care electronic patient-level data. BMJ Open, 2022.

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Health care use attributable to COVID-19: A propensity matched national electronic health records cohort study of 249,390 people in Wales, UK. medRxiv, 2022.

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Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration. 2022.

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Genome-wide association study investigating short and long sleep duration: a cross-population meta-analysis. medRxiv, 2022.

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Genome-wide association study identifies ADRA2A and IRX1 as novel risk genes for Raynaud's phenomenon. medRxiv, 2022.

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Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. Heart, 2022.

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Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study. Cardiovascular Diabetology, 2022.

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Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. European Heart Journal-Quality of Care and Clinical Outcomes, 2022.

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Digital ethnicity data in population-wide electronic health records in England: a description of completeness, coverage, and granularity of diversity. medRxiv, 2022.

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Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease. European Heart Journal, 2022.

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COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records. The Lancet Digital Health, 2022.

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CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research. European heart journal, 2022.

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ClustEHR: a tool for generating synthetic EHR data for unsupervised learning experiments.. International Journal of Population Data Science, 2022.

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Cardiovascular outcomes associated with treatment of type 2 diabetes in patients with ischaemic heart failure. ESC Heart Failure, 2022.

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Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales. Circulation, 2022.

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Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England. PLoS medicine, 2022.

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Association between practice coding of chronic kidney disease (CKD) in primary care and subsequent hospitalisations and death: a cohort analysis using national audit data. BMJ open, 2022.

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Adiposity and grip strength: a Mendelian randomisation study in UK Biobank. BMC medicine, 2022.

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A retrospective cohort study measured predicting and validating the impact of the COVID-19 pandemic in individuals with chronic kidney disease.. Kidney international, 2022.

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A population-based study of 92 clinically recognized risk factors for heart failure: co-occurrence, prognosis and preventive potential. European journal of heart failure, 2022.

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Programme grants for applied research. Using Nationwide ‘Big Data’from Linked Electronic Health Records to Help Improve Outcomes in Cardiovascular Diseases, 2021.

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Enzyme-Inducing Antiseizure Drug Use Is Associated with Long-Term Cardiovascular Disease in a Dose Dependent Fashion in Adults with Epilepsy. Available at SSRN 3831850, 2021.

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Methods for enhancing the reproducibility of biomedical research findings using. 2021.

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data in England.[version 1; referees: awaiting peer review]. 2021.

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Identifying clinically important COPD sub-types using data-driven approaches in primary. 2021.

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A Trainable Model to Assess the Accuracy of Probabilistic Record Linkage. Springer, Cham, 2021.

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Net clinical benefit of warfarin in individuals with atrial fibrillation across stroke risk and across primary and secondary care.. 2021.

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ISAHealth 2016 Organizing Committee. 2021.

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‘What is the risk to me from COVID-19?’: Public involvement in providing mortality risk information for people with ‘high-risk’conditions for COVID-19 (OurRisk. CoV). Clinical Medicine, 2021.

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Weight change and the onset of cardiovascular diseases: emulating trials using electronic health records. Epidemiology (Cambridge, Mass.), 2021.

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Vaccinating adolescents against SARS-CoV-2 in England: a risk--benefit analysis. Journal of the Royal Society of Medicine, 2021.

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Understanding COVID-19 trajectories from a nationwide linked electronic health record cohort of 56 million people: phenotypes, severity, waves & vaccination. medRxiv, 2021.

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Type 2 diabetes and COVID-19--Related mortality in the critical care setting: a national cohort study in England, March--July 2020. Diabetes Care, 2021.

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Transforming and evaluating electronic health record disease phenotyping algorithms using the OMOP common data model: a case study in heart failure. JAMIA Open, 2021.

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The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomisation study in the UK Biobank. Diabetes, 2021.

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The influence of CYP2D6 and CYP2C19 genetic variation on diabetes mellitus risk in people taking antidepressants and antipsychotics.. medRxiv, 2021.

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The genomics of heart failure: design and rationale of the HERMES consortium. ESC heart failure, 2021.

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The association between mechanical ventilator availability and mortality risk in intensive care patients with COVID-19: A national retrospective cohort study. medRxiv, 2021.

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Temporal trends in heart failure medication prescription in a population-based cohort study. BMJ open, 2021.

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Real world evidence on 5661 patients treated for macular oedema secondary to branch retinal vein occlusion with intravitreal anti-vascular endothelial growth factor, intravitreal dexamethasone or macular laser. British Journal of Ophthalmology, 2021.

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Protocol for the development of the Wales Multimorbidity e-Cohort (WMC): data sources and methods to construct a population-based research platform to investigate multimorbidity. BMJ open, 2021.

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Outcomes and risk of reactivation of myopic CNV: Multi-Centre Study with long term follow up. Investigative Ophthalmology & Visual Science, 2021.

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Obesity during the COVID-19 pandemic: both cause of high risk and potential effect of lockdown? A population-based electronic health record study. Public health, 2021.

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Multicentre study of 4626 patients assesses the effectiveness, safety and burden of two categories of treatments for central retinal vein occlusion: intravitreal anti-vascular endothelial growth factor injections and intravitreal Ozurdex injections. British Journal of Ophthalmology, 2021.

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Mapping the Read2/CTV3 controlled clinical terminologies to Phecodes in UK Biobank primary care electronic health records: implementation and evaluation. AMIA Annual Symposium Proceedings, 2021.

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Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility. BMC medicine, 2021.

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Linking electronic health records for research on a nationwide cohort including over 54 million people in England. medRxiv, 2021.

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Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource. bmj, 2021.

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Internal-external cross-validation helped to evaluate the generalizability of prediction models in large clustered datasets. Journal of Clinical Epidemiology, 2021.

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Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study. BMC infectious diseases, 2021.

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Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study-Supplementary material, code and data. OSF, 2021.

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Identifying high-risk groups for change in weight and body mass index: population cohort of 11 million measurements in 2.3 million adults. medRxiv, 2021.

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Identifying and evaluating clinical subtypes of Alzheimer’s disease in care electronic health records using unsupervised machine learning. BMC medical informatics and decision making, 2021.

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Identification and mapping real-world data sources for heart failure, acute coronary syndrome, and atrial fibrillation. Cardiology, 2021.

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Hospital readmission among people experiencing homelessness in England: a cohort study of 2772 matched homeless and housed inpatients. J Epidemiol Community Health, 2021.

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Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis. BMJ open, 2021.

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Feasibility study of hospital antimicrobial stewardship analytics using electronic health records. JAC-Antimicrobial Resistance, 2021.

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Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic. European journal of preventive cardiology, 2021.

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Evolving treatment patterns and outcomes of neovascular age-related macular degeneration over a decade. Ophthalmology Retina, 2021.

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Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. medRxiv, 2021.

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Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic. Circulation: Cardiovascular Quality and Outcomes, 2021.

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Emergency department attendance after telephone triage. International Journal of Population Data Science, 2021.

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Emergency department attendance after telephone triage. International Journal of Population Data Science, 2021.

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Development and Validation of a Primary Care Electronic Health Record Phenotype to Study Migration and Health in the UK. Preprints, 2021.

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Desiderata for the development of next-generation phenotype libraries.. 2021.

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Data-driven identification of ageing-related diseases from electronic health records. Scientific reports, 2021.

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Comparison of risk factors for coronary event in people with unattributed and non-coronary chest pain: an electronic health record cohort study. European Heart Journal, 2021.

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Association of Enzyme-Inducing Antiseizure Drug Use With Long-term Cardiovascular Disease. JAMA neurology, 2021.

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Association of COVID-19 with arterial and venous vascular diseases: a population-wide cohort study of 48 million adults in England and Wales. medRxiv, 2021.

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Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, and thrombocytopenic events: whole population cohort study in 46 million adults in England. medRxiv, 2021.

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Are we doing better? Impact of treatment paradigm change on neovascular age-related macular degeneration treatment outcomes over the past decade. A big data analysis.. Investigative Ophthalmology & Visual Science, 2021.

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An Informatics Consult approach for generating clinical evidence for treatment decisions. medRxiv, 2021.

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A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the remote early detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trial. Trials, 2021.

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A population-based study of 92 clinically recognised risk factors for heart failure: co-occurrence, prognosis and preventive potential. European journal of heart failure, 2021.

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A nationwide deep learning pipeline to predict stroke and COVID-19 death in atrial fibrillation. medRxiv, 2021.

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A national retrospective cohort study of mechanical ventilator availability and its association with mortality risk in intensive care patients with COVID-19. medRxiv, 2021.

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A genetics-first approach to dissecting the heterogeneity of autism: phenotypic comparison of autism risk copy number variants. American Journal of Psychiatry, 2021.

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1 approved with reservations, 1 not approved. 2021.

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Weight change and the incidence of cardiovascular diseases in adults with normal weight, overweight and obesity without chronic diseases; emulating trials using electronic health records. medRxiv, 2020.

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Validity of UK electronic health records to study migrant health: a population-based cohort study. European Journal of Public Health, 2020.

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Using Unsupervised Learning to Identify Clinical Subtypes of Alzheimer's Disease in Electronic Health Records. Studies in health technology and informatics, 2020.

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Type 2 Diabetes and COVID-19--Related Mortality in the Critical Care Setting: A National Cohort Study in England, March--July 2020. Diabetes Care, 2020.

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Trajectories of Disease Accumulation Using Electronic Health Records. Studies in health technology and informatics, 2020.

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The Wales Multi-morbidity e-Cohort (WMC): data sources and methods to construct a population-based research platform to investigate multi-morbidity.. 2020.

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The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK Biobank. medRxiv, 2020.

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The 4C Initiative (Clinical Care for Cardiovascular disease in the COVID-19 pandemic): monitoring the indirect impact of the coronavirus pandemic on services for cardiovascular diseases in the UK. medRxiv, 2020.

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The 4C Initiative (Clinical Care for Cardiovascular disease in the COVID-19 pandemic)--monitoring the indirect impact of the coronavirus pandemic on services for cardiovascular diseases in the UK. medRxiv, 2020.

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Selective recruitment designs for improving observational studies using electronic health records. Statistics in Medicine, 2020.

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Safety of synthetic and biological DMARDs: a systematic literature review informing the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis. Annals of the rheumatic diseases, 2020.

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Real world evidence on 5661 patients treated for macular oedema secondary to branch retinal vein occlusion with intravitreal anti-vascular endothelial growth factor, intravitreal dexamethasone or macular laser. British Journal of Ophthalmology, 2020.

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Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases. Human molecular genetics, 2020.

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Obesity during the COVID-19 pandemic: cause of high risk or an effect of lockdown? A population-based electronic health record analysis in 1 958 184 individuals.. medRxiv, 2020.

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Multicentre study of 4626 patients assesses the effectiveness, safety and burden of two categories of treatments for central retinal vein occlusion: intravitreal anti-vascular endothelial growth factor injections and intravitreal Ozurdex injections. British Journal of Ophthalmology, 2020.

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Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK. Heart, 2020.

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Models for mortality require tailoring in the context of the COVID-19 pandemic--Authors' reply. The Lancet, 2020.

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Lifetime risk of cardiovascular-renal disease in type 2 diabetes: a population-based study in 473399 individuals. European Heart Journal, 2020.

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Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study. Wellcome Open Research, 2020.

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IEA. International Journal of Epidemiology, 2020.

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How to estimate the association between change in a risk factor and a health outcome?. arXiv preprint arXiv:2012.11291, 2020.

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Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England. Wellcome Open Research, 2020.

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Healthcare resource utilisation and mortality outcomes in international migrants to the UK: analysis protocol for a linked population-based cohort study using Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the Office for National Statistics (ONS). Wellcome Open Research, 2020.

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature communications, 2020.

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Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic.. medRxiv, 2020.

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Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic. Circulation: Cardiovascular Quality and Outcomes, 2020.

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Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. The Lancet, 2020.

Cite HDR UK Phenotype Portal OurRisk.Cov excess mortality risk calculator

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study. BMJ Open, 2020.

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Emulating a target trial in case-control designs: an application to statins and colorectal cancer. International Journal of Epidemiology, 2020.

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Electronic Health Records to Predict Gestational Diabetes Risk. Trends in Pharmacological Sciences, 2020.

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Diabetes and COVID-19 Related Mortality in the Critical Care Setting: A Real-Time National Cohort Study in England. Available at SSRN 3615999, 2020.

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Clinical academic research in the time of Corona: a simulation study in England and a call for action. medRxiv, 2020.

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Big data in epilepsy: clinical and research considerations. Report from the Epilepsy Big Data Task Force of the International League Against Epilepsy. Epilepsia, 2020.

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Association of COVID-19 with major arterial and venous thrombotic diseases: a population-wide. System, 2020.

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Antibiotic prescribing in UK care homes 2016--2017: retrospective cohort study of linked data. BMC health services research, 2020.

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An interdisciplinary mixed-methods approach to developing antimicrobial stewardship interventions: Protocol for the Preserving Antibiotics through Safe Stewardship (PASS) Research Programme. Wellcome Open Research, 2020.

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Allergic disease, corticosteroid use, and risk of Hodgkin lymphoma: A United Kingdom nationwide case-control study. Journal of Allergy and Clinical Immunology, 2020.

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A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems.. medRxiv, 2020.

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A national initiative in data science for health: an evaluation of the UK Farr Institute. International journal of population data science, 2020.

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A geotemporal survey of hospital bed saturation across England during the first wave of the COVID-19 Pandemic. medRxiv, 2020.

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92 aetiologic factors for heart failure: prevalence, co-occurrence, prognosis and potential for prevention in 170,885 incident HF cases. European Heart Journal, 2020.

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Validity of using UK primary care electronic health records to study migration and health: a population-based cohort study. The Lancet, 2019.

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UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER. Journal of the American Medical Informatics Association, 2019.

Cite HDR UK Phenotype Portal

The relationship between sleep duration, cognition and dementia: a Mendelian randomization study. International journal of epidemiology, 2019.

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The Centre for Data and Knowledge Integration for Health (CIDACS): Linking Health and Social Data in Brazil. Swansea University, 2019.

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Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis. EP Europace, 2019.

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Socioeconomic deprivation and regional variation in Hodgkin�s lymphoma incidence in the UK: A population-based cohort study of 10 million individuals. BMJ Open, 2019.

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Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records. Rhinology, 2019.

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Risk factors for incident heart failure in age-and sex-specific strata: a population-based cohort using linked electronic health records. European journal of heart failure, 2019.

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Phenotyping UK Electronic Health Records from 15 Million Individuals for Precision Medicine: The CALIBER Resource. Studies in Health Technology and Informatics, 2019.

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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 2019.

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P5705 Machine learning for phenotyping and risk prediction in cardiovascular diseases: a systematic review. European Heart Journal, 2019.

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P1-554 DISCOVERING SUBTYPES OF ALZHEIMER�S DISEASE USING ELECTRONIC HEALTH RECORDS. Alzheimer’s & Dementia, 2019.

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Network Structures and Dynamics Of Early Dementia Events Recorded in Primary Care Electronic Health Records. Proceedings of the 9th International Conference on Digital Public Health, 2019.

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Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death. Journal of biomedical semantics, 2019.

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Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study. Cardiovascular Diabetology, 2019.

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Mental health and behavioural problems in children with XXYY: a comparison with intellectual disabilities. Journal of Intellectual Disability Research, 2019.

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Machine learning for phenotyping and risk prediction in cardiovascular diseases: a systematic review. EUROPEAN HEART JOURNAL, 2019.

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Improving the odds of drug development success through human genomics: modelling study. Scientific Reports, 2019.

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Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records. BMC Medical Informatics and Decision Making, 2019.

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Hospital Readmissions Among People Experiencing Homelessness: A Cohort Study of Linked Hospitalisation and Mortality Data in England for 3,222 Homeless Inpatients. 2019.

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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure. bioRxiv, 2019.

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Exploring hybrid parallel systems for probabilistic record linkage. The Journal of Supercomputing, 2019.

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Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).. 2019.

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Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme). Trials, 2019.

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Employment Cost Index, Historical Listing--Volume V: Continuous Occupational and Industry Series: September 1975-December 2017. Table 4: employment cost index for total compensation, for civilian workers, by occupation and industry: continuous occupational and industry series.. Circulation, 2019.

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Dementia recognition, diagnosis, and treatment in the UK, 1997--2017: a change-point analysis. The Lancet, 2019.

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Classification of atherothrombotic events in myocardial infarctions survivors with supervised machine learning using data from an electronic health record system. International Conference on Informatics, Management and Technology in Healthcare (ICIMTH), 2019.

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Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial. Trials, 2019.

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Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England.. Wellcome open research, 2019.

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Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis. BMC medicine, 2019.

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Avoidable flaws in observational analyses: an application to statins and cancer. Nature Medicine, 2019.

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Associations between measures of sarcopenic obesity and risk of cardiovascular disease and mortality: a cohort study and Mendelian randomization analysis using the UK Biobank. Journal of the American Heart Association, 2019.

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Association of polygenic risk scores for coronary artery disease with subsequent events amongst established cases. medRxiv, 2019.

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Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records. Rhinology, 2019.

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Analyzing the heterogeneity of rule-based EHR phenotyping algorithms in CALIBER and the UK Biobank. BioRxiv, 2019.

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A novel metadata management model to capture consent for record linkage in longitudinal research studies. Informatics for Health and Social Care, 2019.

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A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service. The Lancet Digital Health, 2019.

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Valvular Atrial Fibrillation: Electronic Health Record-Derived Phenotypes, Trends in Prevalence and Prognosis. Circulation, 2018.

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Time spent at blood pressure target and the risk of death and cardiovascular diseases. PloS one, 2018.

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REAL-WORLD DATA SOURCES FOR HEART FAILURE RESEARCH: A SYSTEMATIC REVIEW. Value in Health, 2018.

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On the accuracy and scalability of probabilistic data linkage over the Brazilian 114 million cohort. IEEE journal of biomedical and health informatics, 2018.

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Discovery of Novel COPD Subtypes Via Cluster Analysis of Clinical Features Extracted from Electronic Health Records. D13. IMPROVING DIAGNOSIS, CARE QUALITY, AND ADHERENCE IN COPD, 2018.

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Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database. International Journal of Medical Informatics, 2018.

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Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study. European Journal of Preventive Cardiology, 2018.

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Application of Clinical Concept Embeddings for Heart Failure Prediction in UK EHR data. NIPS ML4H: Machine Learning for Health arXiv preprint arXiv:1811.11005, 2018.

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An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ open, 2018.

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